Cumulative evidence for association of sepsis and retinopathy of prematurity.

ABSTRACT:

Background

Retinopathy of prematurity (ROP) is a retinal vasoproliferative disease affected by multiple factors such as infection and preterm birth. The role of sepsis in the development of ROP remains controversial. This systematic review and meta-analysis aimed to identify the impact of sepsis on ROP.

Methods

The PubMed, Embase, and Cochrane Library databases were searched using terms related to sepsis and ROP. Cohort or case-control studies that reported the association of sepsis and ROP were eligible. The odds ratios (ORs) together with the 95% confidence interval (CI) were extracted from the studies or computed by authors if not provided.

Results

Thirty-four studies were ultimately included in this meta-analysis. The pooled results showed that sepsis increased th

SUBMITTER: Huang J 

PROVIDER: S-EPMC6824763 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature