Dataset Information
The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue.
Ontology highlight
ABSTRACT:
SUBMITTER: Voigt FF
PROVIDER: S-EPMC6824906 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Publications
The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue.
Nature methods 20190916 11
Light-sheet microscopy is an ideal technique for imaging large cleared samples; however, the community is still lacking instruments capable of producing volumetric images of centimeter-sized cleared samples with near-isotropic resolution within minutes. Here, we introduce the mesoscale selective plane-illumination microscopy initiative, an open-hardware project for building and operating a light-sheet microscope that addresses these challenges and is compatible with any type of cleared or expand ...[more]