Identification of key genes involved in the biosynthesis of triterpenic acids in the mint family.

ABSTRACT: Triterpenic acids (TAs), a large group of natural compounds with diverse biological activity, are produced by several plant taxa. Betulinic, oleanolic, and ursolic acids are the most medicinally important TAs and are mainly found in plants of the mint family. Metabolic engineering is strongly dependent on identifying the key genes in biosynthetic pathways toward the products of interest. In this study, gene expression tracking was performed by transcriptome mining, co-expression network analysis, and tissue-specific metabolite-expression analysis in order to identify possible key genes involved in TAs biosynthetic pathways. To this end, taxa-specific degenerate primers of six important genes were designed using an effective method based on the MEME algorithm in a phylogenetically related g

SUBMITTER: Aminfar Z 

PROVIDER: S-EPMC6825174 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature