Connectivity of the human insula: A cortico-cortical evoked potential (CCEP) study.

ABSTRACT:

Objective

The human insula is increasingly being implicated as a multimodal functional network hub involved in a large variety of complex functions. Due to its inconspicuous location and highly vascular anatomy, it has historically been difficult to study. Cortico-cortical evoked potentials (CCEPs), utilize low frequency stimulation to map cerebral networks. They were used to study connections of the human insula.

Methods

CCEP data was acquired from each sub-region of the dominant and non-dominant insula in 30 patients who underwent stereo-EEG. Connectivity strength to the various cortical regions was obtained via a measure of root mean square (RMS), calculated from each gyrus of the insula and ranked into weighted means.

Results

The results of all cumulative CCEP res

SUBMITTER: Dionisio S 

PROVIDER: S-EPMC6825888 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature