Maximum morning home systolic blood pressure is an indicator of the development of diabetic nephropathy: The KAMOGAWA-HBP study.

ABSTRACT:

Aims/introduction

The maximum value of home systolic blood pressure is correlated with damage to target organs, including diabetic nephropathy. However, the precise relationship between the development of diabetic nephropathy and maximum home systolic blood pressure has not been elucidated.

Materials and methods

In this prospective 2-year cohort subanalysis of the KAMOGAWA-HBP study, the patient population was 477 Japanese patients with normoalbuminuria. We investigated the effects of mean and maximum home blood pressure on the development of diabetic nephropathy, which we defined as a urinary albumin excretion value ≥30 mg/g creatinine. Among the 477 patients, 67 developed diabetic nephropathy.

Results

In our multivariate logistic regression analyses, the maximum mor

SUBMITTER: Okamura T 

PROVIDER: S-EPMC6825917 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature