Safety of Ramadan fasting in young patients with type 1 diabetes: A systematic review and meta-analysis.

ABSTRACT:

Aims/introduction

Although patients with type 1 diabetes are medically exempt, many insist on fasting during Ramadan. Multiple daily insulin injections (MDI), premixed insulin and continuous subcutaneous insulin infusion (CSII) are commonly used. To date, little is known about the safety of Ramadan fasting in these patients.

Materials and methods

We pooled data from 17 observational studies involving 1,699 patients treated with either CSII or non-CSII (including premixed and MDI) regimen. The study outcomes were the frequencies of hypoglycemia, hyperglycemia and/or ketosis. Given the lack of patient-level data, separate analyses for premixed and MDI regimen were not carried out.

Results

The CSII-treated group (n = 203) was older (22.9 ± 6.9 vs 17.8 ± 4.0 years), and h

SUBMITTER: Loh HH 

PROVIDER: S-EPMC6825934 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature