Association between APOE polymorphisms and lipid profile in Mexican Amerindian population.

ABSTRACT:

Background

Apolipoprotein E (ApoE) is a glycoprotein that plays an important role in lipid homeostasis at both cerebral and systemic levels. Moreover, the differential distribution of APOE gene alleles among different populations, means that ApoE isoforms could have different effects on lipids metabolism. The present study aims to evaluate the relationship between APOE gene alleles and the lipid profile in a Mexican Amerindian (MA) population.

Methods

This study included 1997 MA individuals of different ethnicities distributed throughout different states of Mexico. All individuals underwent anthropometric measurements as well as laboratory tests including fasting glucose (FG), total cholesterol (TC), triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-densit

SUBMITTER: Martinez-Magana JJ 

PROVIDER: S-EPMC6825948 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature