Population prevalence of individuals meeting criteria for hereditary breast and ovarian cancer testing.

ABSTRACT:

Background

Personal cancer diagnosis and family cancer history factor into which individuals should undergo genetic testing for hereditary breast and ovarian cancer (HBOC) syndrome. Family history is often determined in the research setting through kindreds with disease clusters, or clinically from self-report. The population prevalence of individuals with diagnostic characteristics and/or family cancer history meeting criteria for HBOC testing is unknown.

Methods

Utilizing Surveillance, Epidemiology, and End Results (SEER) cancer registry data and a research resource linking registry records to genealogies, the Utah Population Database, the population-based prevalence of diagnostic and family history characteristics meeting National Comprehensive Cancer Network (NCCN) crite

SUBMITTER: Greenberg S 

PROVIDER: S-EPMC6825998 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature