Paf1c defects challenge the robustness of flower meristem termination in <i>Arabidopsis thaliana</i>.

ABSTRACT: Although accumulating evidence suggests that gene regulation is highly stochastic, genetic screens have successfully uncovered master developmental regulators, questioning the relationship between transcriptional noise and intrinsic robustness of development. To identify developmental modules that are more or less resilient to large-scale genetic perturbations, we used the Arabidopsis polymerase II-associated factor 1 complex (Paf1c) mutant vip3, which is impaired in several RNA polymerase II-dependent transcriptional processes. We found that the control of flower termination was not as robust as classically pictured. In angiosperms, the floral female organs, called carpels, display determinate growth: their development requires the arrest of stem cell maintenance. In vip3

SUBMITTER: Fal K 

PROVIDER: S-EPMC6826038 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature