Racial/ethnic disparities in renal cell carcinoma: Increased risk of early-onset and variation in histologic subtypes.

ABSTRACT:

Background

Racial/ethnic minority groups have a higher burden of renal cell carcinoma (RCC), but RCC among Hispanic Americans (HAs) and American Indians and Alaska Natives (AIs/ANs) are clinically not well characterized. We explored variations in age at diagnosis and frequencies of RCC histologic subtypes across racial/ethnic groups and Hispanic subgroups using National Cancer Database (NCDB) and Arizona Cancer Registry Data.

Methods

Adult RCC cases with known race/ethnicity were included. Logistic regression analysis was performed to estimate odds and 95% confidence interval (CI) of early-onset (age at diagnosis <50 years) and diagnosis with clear cell RCC (ccRCC) or papillary RCC.

Results

A total of 405 073 RCC cases from NCDB and 9751 cases from ACR were identified

SUBMITTER: Batai K 

PROVIDER: S-EPMC6826053 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature