Environmental and Genetic Determinants of Serum 25(OH)-Vitamin D Levels during Pregnancy and Early Childhood.

ABSTRACT: Vitamin D insufficiency has become a common health problem worldwide, particularly among pregnant women and young children. Therefore, we sought to identify environmental, dietary, and genetic determinants of serum 25(OH)-vitamin D (25(OH)D) levels during pregnancy and early childhood. 25(OH)D was measured in women at 24-weeks of gestation (n = 738) and one-week postpartum (n = 284) in the population-based Danish COPSAC₂₀₁₀ mother-child cohort; and in cord blood (n = 257) and age 4 years (n = 298) in children from the at-risk COPSAC₂₀₀₀ mother-child cohort. Environmental, dietary, and genetic variables were tested for association with 25(OH)D using linear regression analyses. After adjusting for season of blood sampling, determinants of low

SUBMITTER: Schoos AM 

PROVIDER: S-EPMC6826446 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature