The association between self-reported poor oral health and gastrointestinal cancer risk in the UK Biobank: A large prospective cohort study.

ABSTRACT:

Background

Controversy remains as to whether poor oral health is independently associated with gastrointestinal cancers, due to potential confounding by smoking, alcohol and poor nutrition. The aim of this study was to investigate the association between oral health conditions and gastrointestinal cancer risk.

Methods

Data from the large, prospective UK Biobank cohort, which includes n = 475,766 participants, were analysed. Cox proportional hazard models were applied to estimate the relationship between gastrointestinal cancer risk and self-reported poor oral health (defined as painful gums, bleeding gums and/or having loose teeth), adjusting for confounders.

Results

During an average six years of follow-up, n = 4069 gastrointestinal cancer cases were de

SUBMITTER: Jordao HW 

PROVIDER: S-EPMC6826526 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature