Telomere Length Changes during Critical Illness: A Prospective, Observational Study.

ABSTRACT: evaluation of telomere length change in acutely ill adult patients. Blood samples were drawn on the first and seventh day of intensive care unit (ICU) stay to assess telomere length using a polymerase chain reaction (PCR)-based technique. Demographic data collected included age, weight, admission diagnosis, baseline laboratory values (pH, C- reactive protein (CRP), serum albumin level, white blood cell count (WBC) count, platelet count), and baseline SOFA and APACHE II scores. Additional data collected during the ICU stay included a repeated WBC count, the presence of positive blood cultures and outcome data, including death in the ICU or following discharge, whether ventilated or not at ICU discharge, and destination following discharge, i.e., medical ward or rehabilitation. General ICU i

SUBMITTER: Zribi B 

PROVIDER: S-EPMC6826589 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature