Bioactive Compounds: Multi-Targeting Silver Bullets for Preventing and Treating Breast Cancer.

ABSTRACT: Each cell in our body is designed with a self-destructive trigger, and if damaged, can happily sacrifice itself for the sake of the body. This process of self-destruction to safeguard the adjacent normal cells is known as programmed cell death or apoptosis. Cancer cells outsmart normal cells and evade apoptosis and it is one of the major hallmarks of cancer. The cardinal quest for anti-cancer drug discovery (bioactive or synthetic compounds) is to be able to re-induce the so called "programmed cell death" in cancer cells. The importance of bioactive compounds as the linchpin of cancer therapeutics is well known as many effective chemotherapeutic drugs such as vincristine, vinblastine, doxorubicin, etoposide and paclitaxel have natural product origins. The present review discusses various b

SUBMITTER: Muniraj N 

PROVIDER: S-EPMC6826729 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature