Variable versus fixed-rate infusion of phenylephrine during cesarean delivery: a randomized controlled trial.

ABSTRACT: BACKGROUND:Phenylephrine is the most commonly used vasopressor for prophylaxis against maternal hypotension during cesarean delivery; however, the best regimen for its administration is not well established. Although variable infusion protocols had been suggested for phenylephrine infusion, evidence-based evaluation of variable infusion regimens are lacking. The aim of this work is to compare variable infusion, fixed on-and-off infusion, and intermittent boluses of phenylephrine for prophylaxis against maternal hypotension during cesarean delivery. METHODS:A randomized controlled study was conducted, including full-term pregnant women scheduled for elective cesarean delivery. Participants were divided into three groups which received phenylephrine by either intermittent boluses (1.5 mcg/Kg

SUBMITTER: Hasanin A 

PROVIDER: S-EPMC6827237 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature