The Linked Selection Signature of Rapid Adaptation in Temporal Genomic Data.

ABSTRACT: The majority of empirical population genetic studies have tried to understand the evolutionary processes that have shaped genetic variation in a single sample taken from a present-day population. However, genomic data collected over tens of generations in both natural and laboratory populations are increasingly used to find selected loci underpinning adaptation over these short timescales. Although these studies have been quite successful in detecting selection on large-effect loci, the fitness differences between individuals are often polygenic, such that selection leads to allele frequency changes that are difficult to distinguish from genetic drift. However, one promising signal comes from polygenic selection's effect on neutral sites that become stochastically associated with the genet

SUBMITTER: Buffalo V 

PROVIDER: S-EPMC6827383 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature