Serum Polyunsaturated Fatty Acids in Middle Childhood and Body Mass Index Change Through Adolescence.

ABSTRACT:

Background

Polyunsaturated fatty acids (PUFA) status in childhood may be associated with adiposity development.

Objective

To assess associations of serum PUFA biomarkers in childhood with change in body mass index (BMI)-for-age Z scores (BMIZ) through adolescence.

Methods

We quantified serum PUFA at ages 5 and 10 years among 418 children from Santiago, Chile. BMI was measured at 5, 10, and 16 years. We compared BMIZ change through age 16 years between quartiles of PUFA at 5 and 10 years and PUFA change 5-10 years by fitting growth curves from mixed effects models.

Results

At age 5 years, serum docosahexaenoic acid was inversely associated with BMIZ change from ages 5 to 16 years. At age 10 years, arachidonic acid (AA) was nonlinearly positively related to BMIZ

SUBMITTER: Flannagan KS 

PROVIDER: S-EPMC6827434 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature