Age-Related Differences in Functional and Structural Connectivity in the Spatial Navigation Brain Network.

ABSTRACT: Spatial navigation involves multiple cognitive processes including multisensory integration, visuospatial coding, memory, and decision-making. These functions are mediated by the interplay of cerebral structures that can be broadly separated into a posterior network (subserving visual and spatial processing) and an anterior network (dedicated to memory and navigation planning). Within these networks, areas such as the hippocampus (HC) are known to be affected by aging and to be associated with cognitive decline and navigation impairments. However, age-related changes in brain connectivity within the spatial navigation network remain to be investigated. For this purpose, we performed a neuroimaging study combining functional and structural connectivity analyses between cerebral regions invo

SUBMITTER: Ramanoel S 

PROVIDER: S-EPMC6828843 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature