Global vs. Network-Specific Regulations as the Source of Intrinsic Coactivations in Resting-State Networks.

ABSTRACT: Spontaneous neural activities are endowed with specific patterning characterized by synchronizations within functionally relevant distant regions that are termed as resting-state networks (RSNs). Although the mechanisms that organize the large-scale neural systems are still largely unknown, recent studies have proposed a hypothesis that network-specific coactivations indeed emerge as the result of globally propagating neural activities with specific paths of transmission. However, the extent to which such a centralized global regulation, rather than network-specific control, contributes to the RSN synchronization remains unknown. In the present study, we investigated the contribution from each mechanism by directly identifying the global as well as local component of resting-state function

SUBMITTER: Amemiya S 

PROVIDER: S-EPMC6829116 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature