Chiral Cocrystal Solid Solutions, Molecular Complexes, and Salts of N-Triphenylacetyl-l-Tyrosine and Diamines.

ABSTRACT: The molecular recognition process and the ability to form multicomponent supramolecular systems have been investigated for the amide of triphenylacetic acid and l-tyrosine (N-triphenylacetyl-l-tyrosine, TrCOTyr). The presence of several supramolecular synthons within the same amide molecule allows the formation of various multicomponent crystals, where TrCOTyr serves as a chiral host. Isostructural crystals of solvates with methanol and ethanol and a series of binary crystalline molecular complexes with selected organic diamines (1,5-naphthyridine, quinoxaline, 4,4'-bipyridyl, and DABCO) were obtained. The structures of the crystals were planned based on non-covalent interactions (O-H···N or N-H+···O- hydrogen bonds) present in a basic structural motif, which is a heterotrimeric building b

SUBMITTER: Czapik A 

PROVIDER: S-EPMC6829379 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature