Abnormalities suggestive of latent tuberculosis infection on chest radiography; how specific are they?

ABSTRACT:

Background

Several radiological features have been reported in association with latent tuberculosis infection (LTBI) but it has not been studied which are specific. The aim of this study was to evaluate allegedly characteristic abnormalities on chest radiography (CXR) in patients with LTBI compared to uninfected controls.

Methods

From 236 patients tested with QuantiFERON-TB Gold In-Tube (QFT), the CXR was re-evaluated in a blinded fashion for fibrotic scarring, (non-)calcified nodules and pleural thickening. LTBI was defined as presence of a positive QFT result and/or positive tuberculin skin test result stratified by Bacille Calmette-Guérin-vaccination status.

Results

Any predefined abnormality of LTBI was observed in 116/236 (49.2%) patients, the frequency not being

SUBMITTER: Uzorka JW 

PROVIDER: S-EPMC6830153 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature