Different molecular characteristics and antimicrobial resistance profiles of Clostridium difficile in the Asia-Pacific region.

ABSTRACT: Molecular epidemiology of Clostridium difficile infection (CDI) has been extensively studied in North America and Europe; however, limited data on CDI are available in the Asia-Pacific region. A multicentre retrospective study was conducted in this region. C. difficile isolates were subjected to multilocus sequence typing (ST) and antimicrobial susceptibility testing. Totally, 394 isolates were collected from Hangzhou, Hong Kong, China; Busan, South Korea; Fukuoka, Japan; Singapore; Perth, Sydney, Australia; New York, the United States. C. difficile isolates included 337 toxin A-positive/B-positive/binary toxin-negative (A⁺B⁺CDT^-), 48 A^-B⁺CDT^-, and nine A⁺B⁺CDT⁺. Distribu

SUBMITTER: Luo Y 

PROVIDER: S-EPMC6830245 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature