Antidepressant use during pregnancy and the risk of gestational diabetes mellitus: a nested case-control study.

ABSTRACT:

Objectives

The aim of this study was to determine the association between antidepressant (AD) classes, types and duration of use during pregnancy and the risk of gestational diabetes mellitus (GDM).

Design and setting

A nested case-control study was conducted within the Quebec Pregnancy Cohort (QPC), a Canadian provincial database which includes data on all pregnancies and children in Quebec from January 1998 to December 2015.

Primary outcome measures

Gestational diabetes mellitus.

Participants

Cases of GDM were identified after week 20 of pregnancy and randomly matched 1:10 to controls on gestational age at index date (ie, calendar date of GDM) and year of pregnancy. AD exposure was assessed by filled prescriptions between the beginning of pregnancy (first day

SUBMITTER: Dandjinou M 

PROVIDER: S-EPMC6830475 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature