Association between syphilis seroprevalence and age among blood donors in Southern China: an observational study from 2014 to 2017.

ABSTRACT: OBJECTIVE:This study investigated the association between syphilis seroprevalence and age among blood donors, and described the distribution of serological titres among syphilis-infected donors, aiming to confirm the syphilis epidemic characteristics and to promote effective interventions for older adults. METHODS:Data were obtained from the Shenzhen Programme for Syphilis Prevention and Control in 2014-2017. Blood samples were screened using the ELISAs, and confirmed using the Treponema pallidum particle agglutination assay (TPPA) and toluidine red unheated serum test (TRUST). RESULTS:Among 394 792 blood donors, 733 tested TPPA and TRUST positive (active infection), and 728 tested only TPPA positive (historical infection). The overall prevalence of syphilis seropositivity was 370.1 per 10

SUBMITTER: Wu X 

PROVIDER: S-EPMC6830658 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature