Effects of different interventions on animal models of ischemic stroke: Protocol for an overview and a network meta-analysis.

ABSTRACT:

Background

Ischemic stroke often leads to lifelong disability or death in stroke patients. It is one of the most common causes of death and disability worldwide, so it is a global health problem. The objective of this protocol is to provide the methods for using overview and network meta-analysis to identify the more effective intervention for infarct volume and neurobehavioral score in animal models of ischemic stroke.

Methods

A systematic literature search will be conducted in PubMed and Embase to obtain relevant systematic reviews on December 11, 2018. Assessing the Methodological Quality of Systematic Reviews (AMSTAR2) and SYRCLE's risk of bias tool will be used to assess quality of the included reviews and risk of bias of randomized controlled trials (RCTs) for animal s

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6831226 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature