Identifying the superior antibiotic prophylaxis strategy for breast surgery: A network meta-analysis.

ABSTRACT:

Background

The clinical roles of different antibiotic prophylaxis strategies for breast surgery remains large unknowns. The aim of this study is to evaluate different antibiotic prophylaxis strategies based on a network meta-analysis.

Methods

We initially retrieved literature from globally recognized databases, namely, MEDLINE, EMBASE and Cochrane Central, to address relative randomized controlled trials (RCTs) investigating the antibiotic prophylaxis strategies for breast surgery. Relative postoperative infection rates were quantitatively pooled and estimated based on the Bayesian theorem. Values of surface under the cumulative ranking curve (SUCRA) probabilities were calculated and ranked. Additional pairwise meta-analyses were performed to validate differences between the

SUBMITTER: Guo T 

PROVIDER: S-EPMC6831324 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature