Genetic and Environmental Influences on the Correlations between Traits of Metabolic Syndrome and CKD.

ABSTRACT: BACKGROUND AND OBJECTIVES:Metabolic syndrome is a cluster of risk factors associated with CKD. By studying the genetic and environmental influences on how traits of metabolic syndrome correlate with CKD, the understanding of the etiological relationships can be improved. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS:From the population-based TwinGene project within the Swedish Twin Registry, 4721 complete twin pairs (9442 European ancestry participants) were included in this cross-sectional twin study. Metabolic syndrome-related continuous traits were measured, and the binary components as well as the status of metabolic syndrome were defined according to the National Cholesterol Education Program-Adult Treatment Panel III. The eGFR was calculated by cystatin C-based equations from the CKD

SUBMITTER: Chen X 

PROVIDER: S-EPMC6832046 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature