A Low-Cost Micro-Volume Nephelometric System for Quantitative Immunoagglutination Assays.

ABSTRACT: Immunoassays have been widely used in scientific research and clinical diagnosis due to their versatile detection capability and high specificity. Immunoagglutination assays are kinds of immunoassay, which can simply and rapidly measure the concentration of analytes. In this work, we developed a low-cost micro-volume nephelometric system for quantitative immunoagglutination assays. We used off-the-shelf components to build the system, and the total cost of key components is only about 20 US dollars. The total detection volume in our system was as low as 3 µL, which could significantly reduce the reagent cost and required sample volume. We further evaluated the system performance via the immunoagglutination assay to measure the concentration of C-reactive protein, a plasma protein with leve

SUBMITTER: Sun Q 

PROVIDER: S-EPMC6832725 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature