BARI 2D: A Reanalysis Focusing on Cardiovascular Events.

ABSTRACT:

Objective

To reanalyze the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial using a new composite cardiovascular disease (CVD) outcome to determine how best to treat patients with type 2 diabetes mellitus and stable coronary artery disease.

Patients and methods

From January 1, 2001, to November 30, 2008, 2368 patients with type 2 diabetes mellitus and angiographically proven coronary artery disease were randomly assigned to insulin-sensitizing (IS) or insulin-providing (IP) therapy and simultaneously to coronary revascularization (REV) or no or delayed REV (intensive medical therapy [MED]), with all patients receiving intensive medical treatment. The outcome of this analysis was a composite of 8 CVD events.

Results

Four-year Kaplan-Meier rates for t

SUBMITTER: Genuth SM 

PROVIDER: S-EPMC6832788 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature