Canine and Phocine Distemper Viruses: Global Spread and Genetic Basis of Jumping Species Barriers.

ABSTRACT: Canine distemper virus (CDV) and phocine distemper (PDV) are closely-related members of the Paramyxoviridae family, genus morbillivirus, in the order Mononegavirales. CDV has a broad host range among carnivores. PDV is thought to be derived from CDV through contact between terrestrial carnivores and seals. PDV has caused extensive mortality in Atlantic seals and other marine mammals, and more recently has spread to the North Pacific Ocean. CDV also infects marine carnivores, and there is evidence of morbillivirus infection of seals and other species in Antarctica. Recently, CDV has spread to felines and other wildlife species in the Serengeti and South Africa. Some CDV vaccines may also have caused wildlife disease. Changes in the virus haemagglutinin (H) protei

SUBMITTER: Kennedy JM 

PROVIDER: S-EPMC6833027 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature