Reconstruction and analysis of a Kluyveromyces marxianus genome-scale metabolic model.

ABSTRACT:

Background

Kluyveromyces marxianus is a thermotolerant yeast with multiple biotechnological potentials for industrial applications, which can metabolize a broad range of carbon sources, including less conventional sugars like lactose, xylose, arabinose and inulin. These phenotypic traits are sustained even up to 45 °C, what makes it a relevant candidate for industrial biotechnology applications, such as ethanol production. It is therefore of much interest to get more insight into the metabolism of this yeast. Recent studies suggested, that thermotolerance is achieved by reducing the number of growth-determining proteins or suppressing oxidative phosphorylation. Here we aimed to find related factors contributing to the thermotolerance of K. marxianus.

Results

Here, we reporte

SUBMITTER: Marcisauskas S 

PROVIDER: S-EPMC6833147 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature