Bedside breath tests in children with abdominal pain: a prospective pilot feasibility study.

ABSTRACT:

Background

There is no definitive method of accurately diagnosing appendicitis before surgery. We evaluated the feasibility of collecting breath samples in children with abdominal pain and gathered preliminary data on the accuracy of breath tests.

Methods

We conducted a prospective pilot study at a large tertiary referral paediatric hospital in the UK. We recruited 50 participants with suspected appendicitis, aged between 5 and 15 years. Five had primary diagnosis of appendicitis. The primary outcome was the number of breath samples collected. We also measured the number of samples processed within 2 h and had CO₂ ≥ 3.5%. Usability was assessed by patient-reported pain pre- and post-sampling and user-reported sampling difficulty. Logistic regression analysis was u

SUBMITTER: Wong DC 

PROVIDER: S-EPMC6833160 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature