Thrombelastometry guided blood-component therapy after cardiac surgery: a randomized study.

ABSTRACT: BACKGROUND:Significant bleeding is a well known complication after cardiac surgical procedures and is associated with worse outcome. Thrombelastometry (ROTEM®) allows point-of-care testing of the coagulation status but only limited data is available yet. The aim was to evaluate the ROTEM®-guided blood component therapy in a randomized trial. METHODS:In case of significant postoperative bleeding (> 200 ml/h) following elective isolated or combined cardiac surgical procedures (including 14% re-do procedures and 4% requiring circulatory arrest) patients were randomized to either a 4-chamber ROTEM®-guided blood-component transfusion protocol or received treatment guided by an algorithm based on standard coagulation testing (control). One hundred four patients (mean age: 67.2 ± 10.4 years, mean

SUBMITTER: Haensig M 

PROVIDER: S-EPMC6833285 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature