Lower Urinary Tract Infections: Management, Outcomes and Risk Factors for Antibiotic Re-prescription in Primary Care.

ABSTRACT:

Background

Urinary tract infections (UTIs) are major drivers of antibiotic prescribing in primary care. Inappropriate antibiotic prescribing for UTIs likely drives antibiotic resistance. We aimed to describe current investigation and antibiotic treatment to examine opportunities for improved antimicrobial stewardship.

Methods

We identified a cohort of all patients with lower UTI diagnosis between 2011 and 2015 in the 390 primary care practices contributing data to ResearchOne in England. We examined investigation, antibiotic treatment and antibiotic re-prescription within 28 days according to guideline-defined patient groups. We assessed risk factors for re-prescription using mixed-effect logistic regression.

Findings

In total, 494,675 UTIs were diagnosed in 300,354 p

SUBMITTER: Pujades-Rodriguez M 

PROVIDER: S-EPMC6833446 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature