Pregnancy Loss and Cancer Risk: A Nationwide Observational Study.

ABSTRACT:

Background

Cancer is the second leading cause of death worldwide. Few studies have investigated if recurrent pregnancy loss is associated with an increased risk of cancer. We aimed to assess whether pregnancy loss is associated with later cancer development.

Methods

We identified all invasive cancers after age 40, among all Danish women born between January 1957 and December 1972, ensuring a full reproductive history. Cases were matched by birth year 1:10 to cancer-free controls. Women were followed until the end of 2017. The number of pregnancy losses (miscarriages or still births) was correlated to long-term cancer risk using conditional logistic regression, providing odds ratios for specific cancers with different numbers of pregnancy losses, all adjusted for age, educati

SUBMITTER: Mikkelsen AP 

PROVIDER: S-EPMC6833468 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature