Impact of Zika Virus Emergence in French Guiana: A Large General Population Seroprevalence Survey.

ABSTRACT:

Background

Since the identification of Zika virus (ZIKV) in Brazil in May 2015, the virus has spread throughout the Americas. However, ZIKV burden in the general population in affected countries remains unknown.

Methods

We conducted a general population survey in the different communities of French Guiana through individual interviews and serologic survey during June-October 2017. All serum samples were tested for anti-ZIKV immunoglobulin G antibodies using a recombinant antigen-based SGERPAxMap microsphere immunoassay, and some of them were further evaluated through anti-ZIKV microneutralization tests.

Results

The overall seroprevalence was estimated at 23.3% (95% confidence interval [CI], 20.9%-25.9%) among 2697 participants, varying from 0% to 45.6% according to mu

SUBMITTER: Flamand C 

PROVIDER: S-EPMC6834069 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature