Adolescent age is an independent risk factor for abnormal spirometry among people living with HIV in Kenya.

ABSTRACT:

Objectives

As life expectancy of people living with HIV (PLWH) improves in low-income and middle-income countries (LMICs), the spectrum of HIV-related pulmonary complications may reflect a greater burden of chronic lung diseases as in high-income countries. We determined whether the risk of abnormal spirometry was greater among adolescent compared with adult PLWH at the Coptic Hope Center for Infectious Diseases in Nairobi, Kenya, and evaluated the role of other cofactors for abnormal spirometry.

Design

We prospectively enrolled adolescent and adult PLWH for this cross-sectional study.

Methods

Data collection included standardized questionnaires, clinical assessment, and prebronchodilator and postbronchodilator spirometry. Adolescents additionally underwent noncontras

SUBMITTER: Attia EF 

PROVIDER: S-EPMC6834296 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature