Patients with high-dose diuretics should get ultrafiltration in the management of decompensated heart failure: a meta-analysis.

ABSTRACT: The identification of specific patients with decompensated heart failure (DHF) who may benefit from ultrafiltration (UF) is important in clinical practice. We undertook a meta-analysis to compare the effects of ultrafiltration and diuretics on major clinical outcomes. The outcomes included weight change, length of hospital stay, rehospitalization for HF, mortality, change in serum creatinine, dialysis dependence, and adverse outcomes. We identified 14 trials including 975 patients with HF, met the eligibility criteria. There was a reduction in heart failure-related rehospitalization in ultrafiltration group when compared with the diuretic group. Subgroup analyses revealed a trend toward the decreased HF readmissions in ultrafiltration plus diuretic therapy group but did not reach statistic

SUBMITTER: Shi X 

PROVIDER: S-EPMC6834743 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature