Conotoxin Diversity in the Venom Gland Transcriptome of the Magician's Cone, Pionoconus magus.

ABSTRACT: The transcriptomes of the venom glands of two individuals of the magician's cone, Pionoconus magus, from Okinawa (Japan) were sequenced, assembled, and annotated. In addition, RNA-seq raw reads available at the SRA database from one additional specimen of P. magus from the Philippines were also assembled and annotated. The total numbers of identified conotoxin precursors and hormones per specimen were 118, 112, and 93. The three individuals shared only five identical sequences whereas the two specimens from Okinawa had 30 sequences in common. The total number of distinct conotoxin precursors and hormones for P. magus was 275, and were assigned to 53 conotoxin precursor and hormone superfamilies, two of which were new based on their divergent signal region. The superfam

SUBMITTER: Pardos-Blas JR 

PROVIDER: S-EPMC6835573 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature