Vitamin D as a Biomarker of Ill Health among the Over-50s: A Systematic Review of Cohort Studies.

ABSTRACT: The association between circulating levels of vitamin D and the incidence of chronic diseases is known. The identification of vitamin D as a biomarker of physiological/pathological ageing could contribute to expanding current knowledge of its involvement in healthy ageing. According to PRISMA guidelines, a systematic review was conducted on cohorts studying the role of 25OH-Vitamin D [25(OH)D] and 1,25(OH)2-Vitamin D [1,25(OH)2D] concentrations as biomarkers of healthy ageing. We consulted MedLine, Scopus, and Web of Science to search for studies on the association between vitamin D status in populations of originally healthy adults, and outcomes of longevity, illness, and physical and cognitive functionality. The quality of the studies was assessed using the Newcastle Ottawa scale. Twenty

SUBMITTER: Caristia S 

PROVIDER: S-EPMC6836048 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature