Anti-Oxidant and Anti-Diabetes Potential of Water-Soluble Chitosan-Glucose Derivatives Produced by Maillard Reaction.

ABSTRACT: Chitosan-sugar derivatives demonstrate some useful biology activities (for example anti-oxidant and anti-microbial activities). In this study, water-soluble chitosan-glucose derivatives (WSCGDs) were produced from a water-soluble chitosan hydrochloride (WSC) with 12.5 kDa of molecular weight and 24.05% of degree of acetylation (DA) via Maillard reaction with the heating temperatures of 100 °C and 121 °C. The Maillard reaction between WSC and glucose was investigated by measuring the absorbances at 420 nm and 294 nm, indicating that the reaction took place more effectively at 121 °C. All WSCGDs exhibited higher anti-oxidant activity than WSC, in which WSCGDs obtained at the treatment 121 °C for 2 h, 3 h, and 4 h expressed the highest ability (IC50 range from 1.90-1.05 mg/mL). Increased anti

SUBMITTER: Tran TN 

PROVIDER: S-EPMC6836137 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature