Use of genetic risks in pediatric organ transplantation listing decisions: A national survey.

ABSTRACT: There is a limited supply of organs for all those who need them for survival. Thus, careful decisions must be made about who is listed for transplant. Studies show that manifesting genetic disease can impact listing eligibility. What has not yet been studied is the impact genetic risks for future disease have on a patient's chance to be listed. Surveys were emailed to 163 pediatric liver, heart, and kidney transplant programs across the United States to elicit views and experiences of key clinicians regarding each program's use of genetic risks (ie, predispositions, positive predictive testing) in listing decisions. Response rate was 42%. Sixty-four percent of programs have required genetic testing for specific indications prior to listing decisions. Sixteen percent have required it withou

SUBMITTER: Graf M 

PROVIDER: S-EPMC6836721 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature