Conceptual similarities between zeolites and artificial enzymes.

ABSTRACT: By using a Diels-Alder (DA) reaction as a base case, we show that a pure silica zeolite acting as an entropy-trapping scaffold can be synthesized with an organic structure directing agent (OSDA) analogue of the transition state (TS) of the DA reaction. A cavity stabilization of the TS is observed with the corresponding decrease in the activation energy of the reaction. A lower enthalpy of activation and a larger decrease in entropy are obtained with the zeolite synthesized with the analogue of the DA TS when compared with other zeolitic structures. Those differences are maintained, while catalytic activity is increased, when active sites are introduced in the zeolite. The catalytic zeolitic system synthesized with the OSDA analogue of the TS shows conceptual similarities with "de novo</

SUBMITTER: Gallego EM 

PROVIDER: S-EPMC6837030 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature