Bivalent AMPA receptor positive allosteric modulators of the bis(pyrimidine) series.

ABSTRACT: The first example of a novel class of AMPA receptor positive allosteric modulators of the bis(pyrimidine) series having a hydroquinone linker has been obtained and showed a potency to increase kainate-induced currents at subnanomolar concentrations.

SUBMITTER: Nazarova AA 

PROVIDER: S-EPMC6837176 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature