Mechanisms involved in the development of diabetic retinopathy induced by oxidative stress.

ABSTRACT:

Background

Diabetic retinopathy (DR) is one of the main complications in patients with diabetes and has been the leading cause of visual loss since 1990. Oxidative stress is a biological process resulting from excessive production of reactive oxygen species (ROS). This process contributes to the development of many diseases and disease complications. ROS interact with various cellular components to induce cell injury. Fortunately, there is an antioxidan t system that protects organisms against ROS. Indeed, when ROS exceed antioxidant capacity, the resulting cell injury can cause diverse physiological and pathological changes that could lead to a disease like DR.

Objective

This paper reviews the possible mechanisms of common and novel biomarkers involved in the development of

SUBMITTER: Guzman DC 

PROVIDER: S-EPMC6837689 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature