Micro/nano-structured TiO2 surface with dual-functional antibacterial effects for biomedical applications.

ABSTRACT: Implant-associated infections are generally difficult to cure owing to the bacterial antibiotic resistance which is attributed to the widespread usage of antibiotics. Given the global threat and increasing influence of antibiotic resistance, there is an urgent demand to explore novel antibacterial strategies other than using antibiotics. Recently, using a certain surface topography to provide a more persistent antibacterial solution attracts more and more attention. However, the clinical application of biomimetic nano-pillar array is not satisfactory, mainly because its antibacterial ability against Gram-positive strain is not good enough. Thus, the pillar array should be equipped with other antibacterial agents to fulfill the bacteriostatic and bactericidal requirements of clinical applic

SUBMITTER: Ge X 

PROVIDER: S-EPMC6838358 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature