Bioinformatic Analysis of the Type VI Secretion System and Its Potential Toxins in the Acinetobacter Genus.

ABSTRACT: Several Acinetobacter strains are important nosocomial pathogens, with Acinetobacter baumannii as the species of greatest concern worldwide due to its multi-drug resistance and recent appearance of hyper-virulent strains in the clinical setting. Acinetobacter colonization of the environment and the host is associated with a multitude of factors which remain poorly characterized. Among them, the secretion systems (SS) encoded by Acinetobacter species confer adaptive advantages depending on the niche occupied. Different SS have been characterized in this group of microorganisms, including T6SS used by several Acinetobacter species to outcompete other bacteria and in some A. baumannii strains for Galleria mellonella colonization. Therefore, to

SUBMITTER: Repizo GD 

PROVIDER: S-EPMC6838775 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature