Long term surgical outcomes for infective endocarditis in people who inject drugs: a systematic review and meta-analysis.

ABSTRACT: BACKGROUND:In recent years, the number of infective endocarditis (IE) cases associated with injection drug use has increased. Clinical guidelines suggest deferring surgery for IE in people who inject drugs (PWID) due to a concern for worse outcomes in comparison to non-injectors (non-PWID). We performed a systematic review and meta-analysis of long-term outcomes in PWID who underwent cardiac surgery and compared these outcomes to non-PWID. METHODS:We systematically searched for studies reported between 1965 and 2018. We used an algorithm to estimate individual patient data (eIPD) from Kaplan-Meier (KM) curves and combined it with published individual patient data (IPD) to analyze long-term outcomes after cardiac surgery for IE in PWID. Our primary outcome was survival. Secondary outcomes w

SUBMITTER: Goodman-Meza D 

PROVIDER: S-EPMC6839097 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature