Observation of Patient and Caregiver Burden Associated with Early Alzheimer's Disease in the United States: Design and Baseline Findings of the GERAS-US Cohort Study1.

ABSTRACT:

Background

Alzheimer's disease (AD) is one of the costliest diseases in the United States.

Objective

To describe aspects of real-world patient and caregiver burden in patients with clinician-diagnosed early AD, including mild cognitive impairment (MCI) and mild dementia (MILD) due to AD.

Methods

Cross-sectional assessment of GERAS-US, a 36-month cohort study of patients seeking care for early AD. Eligible patients were categorized based on study-defined categories of MCI and MILD and by amyloid positivity [+] or negativity [-] within each severity cohort. Demographic characteristics, health-related outcomes, medical history, and caregiver burden by amyloid status are described.

Results

Of 1,198 patients with clinician-diagnosed early AD, 52% were amyloid[+]. Fo

SUBMITTER: Robinson RL 

PROVIDER: S-EPMC6839598 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature