Quantitative assessment of interstitial lung disease in Sjogren's syndrome.

ABSTRACT: BACKGROUND:Interstitial lung disease (ILD) is a frequent manifestation of Sjögren's syndrome (SS), an autoimmune disease of salivary and lacrimal glands, and affects approximately 20% of patients. No clinical or serological features appear to be useful to predict its presence, severity or progression, and chest high-resolution computed tomography (CT) remains the gold standard for diagnosis. Semiquantitative CT (SQCT) based on visual assessment (Goh and Taouli scoring) can estimate ILD extent, although it is burdened by relevant intra- and interobserver variability. Quantitative chest CT (QCT) is a promising alternative modality to assess ILD severity. AIM:To determine whether QCT assessment can identify extensive or limited lung disease in patients with SS and ILD. METHODS:This multi-cent

SUBMITTER: Guisado-Vasco P 

PROVIDER: S-EPMC6839858 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature